Hypo-Osmolar Stress Induces p75NTR Expression by Activating Sp1-Dependent Transcription
نویسندگان
چکیده
منابع مشابه
Hypo-osmolar stress induces p75NTR expression by activating Sp1-dependent transcription.
Injury-induced expression of the p75 neurotrophin receptor (p75NTR) in the CNS facilitates neuronal apoptosis and prevents neuronal regrowth, but the mechanisms regulating p75NTR expression are poorly characterized. In this study, we showed that hypo-osmolarity induces p75NTR expression in primary neurons, and, using a comparative genomics approach, we identified conserved elements in the 25 kb...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2007
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.4806-06.2007